CVE-2024-50636

PyMOL 2.5.0 contains a vulnerability in its "Run Script" function, which allows the execution of arbitrary Python code embedded within .PYM files. Attackers can craft a malicious .PYM file containing a Python reverse shell payload and exploit the function to achieve Remote Command Execution (RCE). This vulnerability arises because PyMOL treats .PYM files as Python scripts without properly validating or restricting the commands within the script, enabling attackers to run unauthorized commands in the context of the user running the application.

• CWE-94

• https://github.com/schrodinger/pymol-open-source/issues/405
• https://github.com/yamerooo123/CVE/blob/main/CVE-2024-50636/Description.md
• https://youtu.be/SWnN_a1tUNc

Published

Nov 11, 2024

Last Modified

Jun 17, 2026

Status

Deferred

• How Strix found a critical auth bypass in etcdStrix autonomously discovered a critical authentication bypass in etcd, later designated CVE-2026-33413.
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